Ashim Matthan: Hi! Everyone. Welcome to the RhinoMight Podcast. My name is Ashim and I’m here with Dr.Kanishka
Dr. Kanishka Jain: Hi! Everyone.
Ashim Matthan: So we’ve taken a small break from our last episode, Episode-4 and this is Episode-5. We’ve had an increase in patient load so we’ve not had much time to record podcast but we want to get quality information out to you guys so we’re gonna try to be more regular with this. And today’s Episode-5 is about a question that we came across on Reddit, a couple of weeks ago and it was about a gentleman who was going to start a Testosterone blast and he wanted to know if his Prolactin levels were going to increase on that blast. Now we’re going to break up the answer to this in like 4 sections The first one is like a short answer. Section-2 is going to be about, ‘How to detect high Prolactin levels’. Section-3 is going to be about ‘How to prevent high Prolactin levels’, and Section-4 is going to be ‘How to reverse high Prolactin levels’. So with that being said the short answer is that while it is extremely rare for Prolactin levels to increase on a Testosterone blast Yes, it can happen. If you are someone who has never ever taken steroids before, never taken any hormones before then it’s very unlikely that you’re going to be experiencing Prolactin levels that go up on a Testosterone blast but if you’re someone who has for example got a history of using Trenbolone or other chemicals then yes you should be worried about Prolactin levels going up. You could be susceptible to that and the reason why this happens is regardless of whichever… which demographic you fall into, the reason why Prolactin levels go up is because your body has a genetic threshold. Now, what happens is when you take Testosterone and you blast Testosterone which is something we’ve covered in previous videos if you blast TEST, your.. your Total Testosterone is going to go up that is going to cause a trigger effect where beyond a certain point, beyond a certain genetically determined threshold which is different for every person once your Testosterone hits that level it’s going to get converted to Estrogen. Then excess Estrogen in turn is going to get converted to Prolactin, and that is how indirectly high Testosterone, Super high, super physiological levels of Testosterone could sometimes get converted to Prolactin. This is how it happens.
Dr. Kanishka Jain: So how to detect it? There are clinical signs which you notice when you have a high Prolactin level, where you have a lack of sex drive, a lack and a loss of libido where your morning erections tend to vanish and things that were exciting and stimulating you don’t excite and stimulate you anymore.
Ashim Matthan: So what Dr.Kanisk is saying is that you’re going to be having.. There are going to be a lot of qualitative changes to your life that you got to be aware of. I think we reiterate this in every single video. But when you’re going to be taking any of these chemicals, when you’re going to be on HRT, TRT or even if you’re just going to be blasting steroids, you have to be hyper aware of yourself. You have to know certain things, You have to know like okay I used to wake up with morning erections every single day and then I go from that to like not even having erections at all. If you go from wanting to have sex regularly to just not be interested in it. If things before that used to arouse you don’t arouse you anymore, you have to be aware. And the second this type of changes take place then yes you have to be really really concerned because it could be Prolactin levels and one of the things that I think.. Dr. Kanishk will also mention is that you could on some rare occasions even suffer from headaches, right?
Dr. Kanishka Jain: Yes. So when you have high levels of Prolactin that can lead to headaches. So in short to cover it, how to detect it? Clinical signs – lack of libido, lack of sex drive, lack of interest in sex, headaches these are the signs that you need to watch out for High Prolactin.
Ashim Matthan: But these are clinical, what else can we do to?
Dr. Kanishka Jain: So the next thing that we can do is get a lab test done Where you do a blood test.. blood checkup for your Prolactin levels. We suggest that you check yourself before you go on a TEST blast and in between if you are susceptible to these kind of issues so you know what was your baseline and what is the value after starting the TEST blast.
Ashim Matthan: Right, right. So exactly, so you are saying to compare. All right, that takes us to the point number three and section-3 is going to be about how to prevent High Prolactin levels and if you are getting high Prolactin levels what you should be taking is; there are three chemicals that you can supplement into your system which will really help you. I’m just going to give you a brief overview of it and then Dr. Kanishka is going to break it down. So you should be taking vitamin B6, you should be taking vitamin E.
Dr. Kanishka Jain: Actually, so to prevent it you would need a high dose of vitamin B6, it can be anywhere between 50 to 100 mg per day. You can also take vitamin E, which we would suggest would be around 30 mg or 400 IUS per day to start with. You may even require up to 600 IUS and something called as S-Adenosyl methionine, which is SAM, which is an over the counter supplement which has also helped in reducing Prolactin level for a lot of patients, and also in prevention. Then the last thing that we come to goes more towards the reversing off the high Prolactin levels, that is Cabergoline.
Ashim Matthan: Right, so the way we would do it is that.. and I think we do this with every single side effect of any chemical that can ever happen is that because you’re going to be hyper aware, now that you know that you should be aware of every little, small thing that could possibly change. So if you’re going to be aware of this, and the second you notice a change, you nip the problem in the bud, you don’t wait for it to fester and You don’t have that attitude.. lackadaisical attitude where you just let the problem grow, right? Or you just assume that it’s just gonna vanish because it’s not. Any side effect that comes in it’s not just a storm that you’re gonna ride out. You know like when.. when we start squatting, and i’m just going to equate this to training for a bit when anybody starts like strength training and they get to a certain level, maybe it’s going to be at like 275 pounds or at some point in your squatting you’re going to go through these like aches and pains in your knees and you’re going to be thinking at that time.. I mean this is for natural lifters and just for like mostly beginners or like not beginners but mostly towards intermediates, whatever you want the label to be, it doesn’t really matter. But the point is that at some threshold they’re going to be like yeah my knee problems are there and I probably want to just wait it out and ride out the pain and it will go away, and yes most times it will but when it comes to chemicals, that attitude cannot translate into this.. it doesn’t work. If you get side effects you’ve got to address it right there and then. and if you get these side effects you should be… if it were up to Dr. Kanishk and me, the way we do it.. Actually, why don’t you talk about how.. how would we do it if in a clinical.. we have these types of cases if a patient comes in and we know that they’ve got a history of Prolactin issues and say this is on a TEST blast this happens to them.
Dr. Kanishka Jain: Yeah. So there are a lot of chemicals that can increase Prolactin levels. Our first job is prevention, where we tell them not to go into those chemicals which are the Nandrolone family, Most likely to cause high Prolactin issues. Then when you are doing a TEST blast you scale up gradually and slowly, you don’t allow these kind of issues to build up overnight. You allow them to come gradually. If they are coming gradually the chemicals that you are supplementing yourself with, they will prevent this. But if this still happens you can run small doses of Cabergoline to control the Prolactin levels. A Cabergoline dose can be around 0.25 which is one tablet or half a tablet a week repeated again after three days and see your effects, like if you’re still getting the lack of sex drive, the lack of libido then the Prolactin levels have not been controlled, you need to cut down on your dose of the Testosterone blast.
Ashim Matthan: So say someone has gone up, say they scaled up from like 0 to 500 which seems to be a really small amount for anybody considering it to be a blast, and say they go to 500 mg a week and they start developing these issues so we will of course put in all these chemicals and then we also start lowering the doses… say 500 goes to 350, 350 goes to 250, all right. And say at 250 there are no problems anymore and then we start scaling it back up, so we normally scale it back up in the same way that we scale down.. like gradually we raise it back up and at that time we hope that the second run of it you’re not going to be getting these issues and the second it happens you know what your threshold is, say it is 420 or whatever.. we we like to do a very frequent dosing so that’s why our number is always like multiples of seven or like six or something like that.
Dr. Kanishka Jain: A good TEST blast would have you flying off the radar or flying.. like achieving things that you thought were not possible like workout to workout you will be beating your PR’s, you will be beating the reps Yeah. And that’s how you know that the TRT or the Testosterone blast is working for you.
Ashim Matthan: Yeah, that’s not really TRT that’s the Testosterone blast.
Dr. Kanishka Jain: Yeah.
Ashim Matthan: But even on TRT you should be like flying way above what you were normally flying at a zero. So there’s always that.. um Yeah so I think that we’ve covered everything to do with Prolactin, and just to wrap this just do a quick summary so everybody who’s tuned in like gets the final gist of it.
Dr. Kanishka Jain: Yes. So, we covered this in four parts: Can Prolactin levels rise on a TEST blast? Yes they can. Can it be detected? Yes it can be detected with clinical signs. We have lack of libido, lack of sex drive, sometimes headaches. Then third is how do you can prevent it? You can take vitamin E, you can take vitamin B6, you can also take something called as SAM and Cabergoline. Cabergoline goes towards the treatment. So if you were to treat it, you would reduce your dose of the Testosterone blast and you would take Cabergoline once or twice a week till your levels are normal or you feel good at a lower dose without the.. without the need of Cabergoline.
Ashim Matthan: Right. And there’s another thing that I want to mention is that people who are prone to Prolactinemia, Testosterone is a wonderful solution to it.. um.. and if you are running Testosterone over a period of time as long as you are running it within TRT limits which is when you’re not blasting, keep in mind this question was about a blast. This question was not about someone who was just taking TRT levels of TEST and all. It was about someone was considering blasting Testosterone, so if you’re going to be blasting it and you know that you’ve got these issues it would be better to not blast and to just run a TRT version of Testosterone or TRT dosage of Testosterone for a longer period of time and you’ll probably still get like really good effects.
Dr. Kanishka Jain: Yes.
Ashim Matthan: Right?.. I think we’ve covered everything and thanks a lot for.. uh.. for listening to us and we hope to see you soon. Thank You.
Dr. Kanishka Jain: Bye.
Ashim Matthan: Hi everyone. Welcome to the RhinoMight podcast. My name is Ashim. This is Dr. Kanishka. Today is episode-4 of this podcast, and we are going to be talking about the difference in HGH dosing for men and women.
Dr. Kanishka Jain: So we would like to divide this into three section. One, is there a difference between the dosing? Number two, why is there a difference? and number three, what would be our recommendations?
Ashim Matthan: Right, how would we go about it. And so let’s get to the first question of is there going to be difference. So if you have a 100kg woman and 100kg man is there going to be a difference in HGH dosing for both of them just based on just this information, nothing else. Not about whether someone is a hyper responder, none of that stuff. Just take it as a simple straight forward scenario 100 kg woman, 100 kg man. Is there going to be a difference in HGH dosing.
Dr. Kanishka Jain: Assuming that both of them have a Growth Hormone deficiency there would be no dose difference.
Ashim Matthan: Correct. Now here’s where the subtleties come in where they’re going to where there is a lot of individual case that comes into play. We hear stories… We’ve heard over the years all these horror stories and sometimes just highly-highly publicized stories about men who take 20 IUs of GH, 30 IUs of GH sometimes and then of course all these pros after they take 30 IUs of GH, they come down and they say hey just take one or two of Pharma grade. But let’s not get into that. That’s a separate video. What we should talk about is that you hear stories about men taking big dosages. You don’t hear so much about women. And yes, on the surface actually women don’t need to take such high dosages but that’s not because they’re women or anything like that. It’s just that your dose is dependent on your body weight and on average if you look at the data pool that is there, on average women weigh less than men. So because on average women weigh less than men and the calculation and all the research work that has been done almost including the huge study that was done in Japan, it’s all dependent on body weight. So in general whether you’re looking at a 0.3 multiple per lean body mass or 0.5 or whatever you want to play with with it’s all dependent on the individual’s body weight and on average women weigh less than men.
Dr. Kanishka Jain: Correct. And then of course especially for women in our clinical practice also we see women taking HRT and being hyper responders to it.
Ashim Matthan: Across the board all HRT.
Dr. Kanishka Jain: All… all hormones. For every single hormone that is there in the body they respond much higher than men.
Ashim Matthan: Right. So even if you look at.. this is little bit off-topic but say for example we’re looking at testosterone. You give a guy say 200 mg of tests. His values might jump up to whatever it comes up to like say 1000, 1200.. that’s like a six time multiple, right 200 to 1200, that a five or six time multiple. With women you give them like 5 or 10 mg and it jumps up to like and that’s going to be like a huge.. that’s like a 15 time multiple sometimes. Yeah 15 to 20 times multiple.
Dr. Kanishka Jain: Right. So… That’s for an average.
Ashim Matthan: An average dose.. right, of course. This is all within therapeutic ranges and stuff like that but let’s.. I just wanted to explain and illustrate actually of how this works. Now human Growth Hormone is a bioidentical hormone. If you have you go to your IGF-1 level tests you find out that there is..that I am on the lower side of the reference range I have deficiency what is it called the actual legal term for it?
Dr. Kanishka Jain: For adults it would be called as Adult Growth Hormone Deficiency called AGHD.
Ashim Matthan: Yes. Correct. That acronym, it’s little difficult. But it’s Adult Growth Hormone Deficiency and if you have AGHD… yes if you have that then you’re a… and then you are liable.. you are a legitimate candidate for Growth Hormone treatment for Growth Hormone Treatment. Correct. Within your HRT.
Dr. Kanishka Jain: So the third part of the video which was – What are our recommendations for Growth Hormone dosing.
Ashim Matthan: Correct. So believe me that’s what I was going to say. If you have.. whether you are man or a woman all of these numbers at the end of the day.. This was the textbook definition This was the textbook definition of how Growth Hormone Treatment should be done which is by body weight, etc. etc. But that’s not really how it works in practice at all. Because in practice the way you go about it is that you always want to play on the safer side. That’s one. And two, you always want to work with the reality of the situation. So if someone wants to take Growth Hormone we’d recommend start off at like a really low dose. Maybe, there would be like a difference again between depending on the patient in front of us whether on their body weight or we might recommend for women you take like say just 0.5 IU Or just one click of your pen and for women.. sorry and for man we might recommend say one more IU to start with but that’s how we start right. We start with 1 IU a week or 0.5 IU a week, start small.
Dr. Kanishka Jain: 1 IU or 0.5 IU per day.
Ashim Matthan: Per day. Sorry.. Per day per week. You start off something small like this. Then in the second week you jump it up a little bit like really tiny maybe you go from one click to two clicks. Correct. So what you are saying is 0.5 to 0.75 IUs. Yes. And you would, okay. So let’s talk about one other thing, the elephant in the room there are many, many GH protocols that are out there. I know a lot of you who are experienced lifters and people who are in this life will want to know like which is the best GH protocol. There is no best GH protocol. There is no worst GH protocol either. It’s just about what works for you at that time and you have to be adaptable to the reality of that situation. So if you say for example so there are these protocols. There’s like 2 on 1 off, 3 on 1 off, 5 on 2 off all seven days at a time.
Dr. Kanishka Jain: Dosing alternate days.
Ashim Matthan: Dosing alternate days twice a day dosing. There are many, many ways to play with this. So you have to first figure out that what is sustainable to your lifestyle. Remember we’re looking at this from an HRT or a therapeutic standpoint, we’re not looking at this from a bodybuilding standpoint. This is not about getting particular results. It’s just about getting the best type of therapeutic advantage for you which is also sustainable like if for example you really hate injections you don’t like needles at all you’re very scared of it. Then telling you do twice a day just because it might be the most efficient way for you that’s not going to work at the end of the day because you’re not going to be able to sustain that. So in that case you would want to do say once every other day, Right?
Dr. Kanishka Jain: Yeah. You want to do every alternate days to start with it and observe the benefits of it. If you’re still not getting the benefits of it you might want to up your dose or you might want to change the frequency.
Ashim Matthan: Okay. So if we see you select on a protocol any one of them that is sustainable to your lifestyle, that is good for you, you select it now. Now let’s work with that assumption that has been selected. We would recommend that you start with something really conservative something really small say 0.5 or 1 IU. Next week you increase it a little bit and then the following week we increase it again and you keep increasing it a little bit at a time till you notice that there are clinical signs of side effects taking place and once those side-effects kick in and we’re getting into the side effects in a second. I want you to talk about it please. And the the second you notice these side effects you start scaling back down. So you don’t stop. A lot of people make a mistake when they just immediately stop taking GH. That’s not good for your system. Don’t stop anything. Just taper it down a little bit and down to like a really tiny dose. So you might have gone up to say 4 IUs a day for example and you might go back down all the way to 0.5 IUs a day and at that stage over a period of time you might notice that your mind, side effects are disappearing and you wait for that and then you might want to stop or you might want to continue and then ramp it back up. All these options are there on the table for you.
Dr. Kanishka Jain: What we are trying to say is much more.. I’m just trying to simplify what you’re saying.. is that that Growth Hormone can cause side effects but they are reversible and they are dose dependent. Yes. So let’s talk about the side effects. So some of the side effects that may happen when we have. when you have reached the peak limit of your Growth Hormone or peak tolerable dose for your body is that you will start noticing tingling in your hands and fingers. This is because of Edema or water retention happening underneath the skin. pressing on the nerves on your hand Then you may notice that a slight growth of your jaw bones or of your eyebrows. You may start noticing that. This becomes very evident especially in the cases of women where they are able to notice this on a day-to-day basis where they observe themselves much more closely than men.
Ashim Matthan: Right. So it’s when you say eyebrows you mean like the skull, right? The skull.
Dr. Kanishka Jain: Yeah. The skull, the bones on the skull, basically they grow, these are the things. These are the things. These are the brows – the Neanderthal look that tends to come in when you start having growth overhere on your eyebrows.
Ashim Matthan: Correct. So exactly and women tend to notice this more so what we know what we, in our experience what we know is that say for example even though everything is body weight dependent and on the surface there is no difference in the dosage between men and women and nor should there be because women are hyper responders and the side effects tend to be more noticeable and unappealing for them because of that we tend to never ever recommend very, very high dosages from them right from the beginning. It might be even extreme circumstances we might say that for a guy.. hey take two IUs a day it could be hypothetically we would say 2 IUs a day but sorry guys I don’t want to jump into that for a woman unless of course she is suffering from major weight gain situation where she’s very, very heavy and she needs to lose weight okay.
Dr. Kanishka Jain: Or she has very, very low IGF level.
Ashim Matthan: Exactly. So someone probably very, very old also could be recommended because their IGF levels are really, really, really low.
Dr. Kanishka Jain: And as women age their tendency to respond to hormones also reduces.
Ashim Matthan: Correct. Yeah, exactly. So the tolerance the… the sensitivity makes a difference how fast and how efficient the body is at liking hormones because what we found is that some.. every person I would say has at least one hormone that really agrees with them and that it agrees with you because you’re able to and this is not… this is going to be slightly out of HRT boundaries almost to the point of like when you’re literally dabbling in say for example what would be legally classified as dangerous territory when you are able to sustain really high dosages of that chemical and not have any side-effects. You know when that happens that okay my body really likes this chemical. It has an affinity for it. It’s not going to harm me and it’s important to know and for some women like Growth Hormones for some people Growth Hormone is one of them that it just works beautifully. They will get the cosmetic benefits of it very, very quickly. They will see a huge improvement in hair quality. Improvement in hair quality.
Dr. Kanishka Jain: Improvement in skin quality. Improvement in signs of aging like if you have had loose skin it will become tight.
Ashim Matthan: Right so this is when we’re going to go slightly off topic Let’s say I don’t know that we’ve done this and I want to talk about this but it’s a little bit off topic I hope that till this point we answer the question that was asked to us. This is going to be again off-topic If someone comes… and then they’ve been having, they’ve taken a lot of DHTs They experience some amount of hair fall, or a lot of hair fall and they’re unhappy with it and they want to reverse Along with all the other hair loss prevention treatments that are there, Growth Hormone is also lumped in with this, right?
Dr. Kanishka Jain: Yeah. Growth hormone would help in recovery of the cells which have been damaged because of that over exposure to DHTs.
Ashim Matthan: Okay. So Growth Hormone is for multiple purposes. It’s a true healer.
Dr. Kanishka Jain: Yeah it’s a true healer while it will also improve the quality of this skin, the hair and everything to do with the hair loss should start reversing with Growth Hormone.
Ashim Matthan: And if just, I know there will be women who are watching this and if they want to know whether the dose of GH is becoming too much for them what you need to do, From what I understand… correct me if I am wrong please, what you need to do is be very, very critical of how you look in the sense that the second you start noticing all the signs of high GH you’ve got to start tapering it back down. That means if you notice water retention under the skin, Carpal Tunnel Syndrome where your wrists and your fingers start tingling or paining, if you start noticing a growth in your jawbone in your actual cranial structure your skull is going to, the bones are going to start changing. When that starts happening and you notice that that it is happening, you got to know that you have entered into the realm of GH has been too high. Your dose is too much. And you need to like taper back down and let allow your IGF-1 levels come down. And once they have come down you can do blood test at that stage to know exactly where you’re at and it’s important to know because if you do you now know both sides of the equation. You know the clinical side of where of what your body can tolerate at XYZ dose whatever the dose is and you also know the exact lab value of what your IGF-1 levels are at that dose which is unhealthy for you. Right.
Dr. Kanishka Jain: Correct.
Ashim Matthan: The Growth Hormone is extreme safe and it’s a wonderful bioidentical hormone in our bodies and we do recommend it and the bottom line is that there is no difference in the dosages between men and women. It’s all about the individual, their responsiveness to GH where women are hypersensitive, and the overall dose of GH is all about body weight.
Dr. Kanishka Jain: Yes it is.
Ashim Matthan: Have we missed anything?
Dr. Kanishka Jain: I don’t think so.
Ashim Matthan: Alright. So thanks a lot for watching this video guys and please ask us your questions and the contact details to ask us these questions is in the slide after this. So thanks a lot. Thanks for watching. Bye!
Ashim Matthan: Hi everyone. Welcome to the RhinoMight Podcast. My name is Ashim. This is Dr. Kanishka. A few videos ago, we spoke about Proviron being a very poor Aromatase Inhibitor, and this video is going to be about how to use Proviron correctly. Proviron is classified as a DHT derivative. It is one of two legally available DHT derivatives. The other one being Stanozolol, which is Winstrol. Both of these are in pill format and oral, so you can consume them orally. And they are both fantastic compounds. This discussion in this video is going to be about Proviron and which is also called Mesterolone, and how do you use Proviron correctly?
Dr. Kanishka Jain: So when do you use Proviron? Proviron is an amazing sidekick to any Testosterone or any Anabolic cycle which is being run.
Ashim Matthan: What it does is that it goes into your… so we have.. all of us have an SHBG, which is Sex Hormone Binding Globulin, and SHBG holds on to Testosterone. It is also a reserve of Testosterone. Now the thing is that if it is within healthy parameters, that’s fine and that’s okay. The problem is that when you are on TRT after a period of time for some people your SHBG value just keeps increasing and increasing and increasing, and your SHBG is holding on to more and more Testosterone and not allowing it to be free. So what this means is that it’s not… you are not getting the full benefits of TRT, of your Testosterone cycle. So you want to take Proviron at that time because it’s going to crash your SHBG. It’s going to force your SHBG to realize Testosterone in the form of free Testosterone, and that free Testosterone is going to have benefits, one which is cosmetic, two all the health benefits of what Testosterone brings as being a great healer; and three, it’s going to increase your sex life.
Dr. Kanishka Jain: In addition, how do you notice that your SHBG is high? One is by Blood Test that is the most accurate form of doing it. And the second that you can do is that let’s say that 200 mg of Testosterone was giving you very good results and suddenly that dose stops working for you. You know that the 200 mg in the past had given you very good results and the dose has stopped working. It means that SHBG has SHBG has increased.
Ashim Matthan: Yeah, most likely.
Dr. Kanishka Jain: Most likely. That is the scenario. So running Proviron at that time would help.
Ashim Matthan: Exactly and you can do either a Blood Test of SHBG or you can do a Blood Test of free Testosterone. They are they are two sides of the same coin, and they both cost almost the same. So just doing one of the two is enough to give you a good understanding of what the scenerio is like.
Dr. Kanishka Jain: Yes. So what are the side-effects of Proviron?
Ashim Matthan: When you have a lot of Proviron and you… of course, this is dose dependent and it’s also dependent on individual to individual. These are all guidelines. At the end of the day, every single patient, every single person that is on TRT is an independent case. So with all those caveats in that, those disclaimers set aside, what we would say is that you are going to have the same basic problems that have… that would happen with any DHT, which is hair fall and acne. So you want to always be careful about this. If your dose hits the threshold limit relative to you, you are going to start experiencing acne and hair fall. The next thing which is the thing that is scary and which I want you to talk about especially because you are a doctor, so issue you should definitely talk about this is prostate issues. When you have a lot of Proviron, you are going to have prostate swelling. And a lot of people gets scared with prostate swelling and prostate cancer, and I want just to clear this up. Like how it should be.
Dr. Kanishka Jain: So prostate swelling is not the same as prostate cancer. Prostate swelling can lead to prostate cancer when not addressed. So if prostate swelling is there, you will notice that your urine stream becomes very, very small. You will have to put more force to evacuate your bladder, and you will have to keep on going to the urine to pass urine very frequently. So these are the two signs that you have to be aware of when running Proviron or any DHT for the matter of fact.
Ashim Matthan: So these are the clinical signs. This is how you know yourself. You have to always self-monitor. Whenever you are taking any of these chemicals, you got to be like hyper aware of yourself. You cannot be laid back and complacent. Even if you are taking something as small as Testosterone even with bioidentical every always pitch about it. That doesn’t mean that you take it like lying down. You are just unaware of things. You should be aware, and this is one of the things that you should know especially if you’ve got to add chemicals to Testosterone. So Proviron is an added chemical. You should know the side effects and you should know what to look out for. You are not going to go running for a Blood Test every single time. It costs a lot of money.
Dr. Kanishka Jain: In addition, if you get balding or you get acne or you get any of these symptoms with just Testosterone alone, then Proviron is not a option for you.
Ashim Matthan: It’s not a good option, and also if ever you get a prostate enlargement and you get prostate swelling or you get your acne or you get hair fall, if any of these side effects are happening, just stop. Stop your dose, gradually lower it, like skip a couple of doses and then slowly, slowly taper it off. And in doing that if you because you are hyper aware and you doing it at the right and you are making the change quickly, all of this will reverse itself. You don’t have to do anything on top of this to reverse this. In short.
Dr. Kanishka Jain: Yeah. As long as you are aware of it and you allow it to be… allow these problems to persist for a long period of time, you will not get the side effects which are going to be permanent.
Ashim Matthan: Exactly. And this, so there are two things that I want to discuss. One is the alternatives to Proviron. If you… or rather why do we use Proviron when there are other alternatives? Like another great alternative is Masteron and Masteron is fantastic because it has lot more cosmetic effects. It’s going to give you that lean hardness that you want in your muscles. And it’s also, I mean, if you have Masteron then very few people will go.. pull-off a Proviron. The thing is that Masteron is not readily available. I don’t think any pharmacy keeps it. I don’t think any doctors also provide a prescription for it. With that… but Masteron is a fantastic chemical as well. The only drawback is that it is an injectable. And for anybody who is on TRT who is doing frequent dosing, micro-dosing of TRT, they don’t want to become a pin cushion where they take multiple shots, they take bigger and bigger injections. You want to keep things simple. So Masteron is not an alternative. That’s why people don’t go for that. Yeah.
Dr. Kanishka Jain: But Masteron is a stronger Anabolic than Proviron.
Ashim Matthan: Exactly. So if you could… so if you have to choose like between running Proviron, let’s say that we take Test or the equations. There is not Test. There is no base, nothing. If you are going to take either of these two chemicals just by itself which one is going to be better for you.. like for anyone?
Dr. Kanishka Jain: Proviron is a weak Anabolic. It is not going to cause any cosmetic changes on its own, while Masteron on its own will cause cosmetic changes where it can literally dry you out and give you that lean, hard look.
Ashim Matthan: Exactly. And as far as triggering that sex drive, Masteron is much better.
Dr. Kanishka Jain: Yeah. Masteron goes and works on the lizard brain as such and causes increased sex drive.
Ashim Matthan: Exactly. So one of the thing that.. and we will save this for another video but one of the things that happens when you take, and this is little bit off-topic, one of the things that happens is when you take like all the Nandrolone compounds that have neuro… Degenerative issues.
Dr. Kanishka Jain: Yeah.
Ashim Matthan: They have Neurodegenerative issues and they also affect your hormone, they are mood enhancers and also they do affect your mood. So whenever you take any of those, it’s always a risk of chemical castration and whenever that happens you see lot of people who takes cycles of Test-Tren-Mast. So Mast is added in to make sure that whatever chemical castration that might take place…
Dr. Kanishka Jain: You get Tren Dick. Yeah.
Ashim Matthan: Exactly. So whatever chemical imbalance of chemical castration that might happen with Tren, Masteron is going to reverse it. So Masteron is super powerful.
Dr. Kanishka Jain: In that sense.
Ashim Matthan: In that sense. And this leads us to the final topic that I wanted to… I wanted us to talk in this video, and that is dosages of Proviron. Now keep in mind, before Kanishka gets into this, just keep in mind that everybody is independent. We said that again. So all those caveats apply especially to dosages. Only thing I would want to say is that you don’t want to exceed 100 mg a day ever because 100 mg seems to be the general threshold at which point all of these side effects come in, in a very aggressive manner and nobody should have to deal with that. So it’s not safe. You are not playing it safe anymore. Over 100 mg means you are floating with danger.
Dr. Kanishka Jain: And in addition to that we wouldn’t want to run Proviron for more than five to six months at a time.
Ashim Matthan: Yeah.
Dr. Kanishka Jain: We don’t do that. It is based on how your body responds to it. So Proviron comes as 25 mg tablets. You would want to start at the most conservative dose, which we feel is half a tablet morning and half a tablet at night. That equals to 25 mg a day or one tablet in a day. And you can slowly, slowly scale it up to one tablet in the morning, half a tablet at night or one morning, one tablet in the morning, one tablet at night, and then slowly, slowly gradually taper it up to 100 mg where you are taking two tablets in the morning, two tablets at night. But we would not exceed anything above that.
Ashim Matthan: How do I know when I should increase the dose? Like how do I know that this 12.5, 12.5 isn’t enough?
Dr. Kanishka Jain: So you know that on the same Testosterone dosing that what effects you are getting. You start feeling the same effects, plus your sex rate picks up. So one of the things that Proviron does do is it improves Libido. A lot of people on TRT when they have high SHBG suffered from low Libido because of the free Testosterone being low.
Ashim Matthan: Right. So it’s going to be qualitative. I have to be self-aware. I mean, like people have to be self-aware when they take this chemical and then they have to be able to gauge when they have, our patients have us, but in general, whenever someone is taking Proviron and you want to self-administer it, then you got to be that much more hyper aware of how to… of all these other things going on and gauge accordingly, right? –
Yes.
Ashim Matthan: Okay. I want to bring out one other thing and that is that we always want to start really, really small with whatever it is that you are doing. Whichever chemical that you are going to add, this is like a… this is not in just related to Proviron in general, we want to start it like a small dose, and you want to keep working upwards. So say even if it’s, for example, and this is way off-topic, but I just feel it’s important that we should mention this. If it’s Winstrol, you want to start Winstrol also at like say 25 mg, three times a week, injectable Winstrol, for example. You want to take 25 mg three times a week, which is sometimes laughable. Lot of people would find this extremely conservative and they’d be like this is not going to do anything for me. And maybe that’s true. Maybe that’s true. For some people, it’s not going to do anything. But you want to start at 25 three times a week and make it like say 50 three times a week, then 75 three times a week, and go up to a point where you know that your body is showing all the side effects that are there. So you should know the side effects of whatever chemical that you are taking. And the second, You start feeling it. That means that your are now flirting with danger. This is your threshold limit for your body and maybe start to cut back down or not, stay at this dose, beyond a certain point.
Dr. Kanishka Jain: Yeah. Because you are allowing your body to understand the chemical, and after understanding the dose that works for you, when you repeat this cycle, you don’t need to go the conservative route again. You can start at that dose.
Ashim Matthan: Yeah. So now we have kind of like getting into next steroid cycle theory. But since we are talking about DHTs and Winstrol, see I take, Am I accurate in making this statement that if I take Winstrol, and I slowly, slowly taper it upwards and I get to say whatever amount is good for me, and now I know that side effects are going to start taking place, if say at this dose I say I’m going to start cutting it back because, you know side effects are there, at that stage I finished my cycle. Let’s say it’s a six weeks cycle. I finished it. It’s put back and I am still on TRT because we love Blasting and Cruising. We don’t like all these cycles. So I’m still on Testosterone. Will that Testosterone heal all of my receptors because, you know, like DHT is down regulate. Yeah. If 100 mg work now, I will need more later on down the line. But if I’m off it for enough time and if I am taking Testosterone, will Testosterone heal this?
Dr. Kanishka Jain: So by healing what you mean is that do they refresh the DHT receptors? So Testosterone what it does is it changes the gene expression to make more androgen receptors. So when there are more androgen receptors, which respond to DHTs like Winstrol, let’s say that you scale back on the Winstrol. There is something which is not going to act on those receptors. It will act with the Testosterone. So it will be more susceptible to Winstrol the next time that you take it. So it will be ready for the same dosage again. Maybe you may not need to take the same higher dose, for the same effects.
Ashim Matthan: Okay. And similarly since I want to circle back to Proviron. We talked about how we don’t allow any of our patients ever exceed five to six months, should they medically require Proviron, and we administer it, we recommend it and prescribe it. And then they take it for whatever five to six months, and then we stop. Normally, why is it that we stop? So this is why we stop for just a few months, and then we observe, and they are also supposed to observe with, you know, clinical means that we just discussed of whether their SHBG is again rising, whether they are going through that problem again with SHBG holding on to Test. And if that is happening, you repeat the process again. So you could very well be like say, for example, 5 months ON, 2-3 months OFF, 5 months ON, 2-3 months OFF. You could keep going up and down on this.
Dr. Kanishka Jain: Yeah. You could do that. You could do it like in a wave pattern where you are on Proviron for a certain amount of time. Then you take it off. Also what you can do is you can modulate it with diet. So if you are on diet, which are going to cause high SHBG like a Keto diet, you can do it with Proviron along with it and get maximum results from your diet.
Ashim Matthan: Right. Because Keto will cause your SHBG to rise and Proviron is counter acting on that, breaking it down. So getting the benefits of Keto plus you are getting the benefits of Proviron freeing up Testosterone and therefore you are getting the best bang for your buck.
Dr. Kanishka Jain: Yes.
Ashim Matthan: And you also have a Test running at the same time.
Dr. Kanishka Jain: Exactly.
Ashim Matthan: So it is the best combination that you could run should you encounter high SHBG while you are running Testosterone on TRT dosages. -Right? –
Dr. Kanishka Jain: Correct.
Ashim Matthan: So I think we summarized this well. If you guys have any questions, please feel free to ask us. Thank you very much for watching this video.
Dr. Kanishka Jain: Bye.
Ashim Matthan: Bye bye.
Ashim Matthan: Hi everyone. Welcome to the RhinoMight podcast. My name is Ashim, this is Dr. Kanishka.
Kanishka Jain: Today’s question is that if you’re running a Test blast, can you use Proviron as an Aromatase Inhibitor along with it?
Ashim Matthan: Right. So the gentleman in question is from Reddit. And he is currently cruising on TRT so he’s on Test. And he’s going to be transitioning from TRT levels of Test to a blast. And he has stockpile Proviron. So, he wants to know if you can use that as an AI. And before we get into this, we should probably consider various aspects of this question. So we’ll go about in a structured manner. We’ll talk about what a Test blast is. We’ll talk about what AI’s are, we’ll talk about DHTs and then we’ll get to the actual question of whether the Proviron is a good AI.
Kanishka Jain: Yes, so before that we have to first start with what is a Test blast. A Test blast is any dose of Testosterone which exceeds your weekly TRT dose. So, usually your TRT dose ranges from anywhere between 100 milligrams a week, to 300 milligrams a week. So, anything in excess of that is called as a Test blast.
Ashim Matthan: Right, and then you can go up to whatever exorbitant levels that bodybuilders push this to.
Kanishka Jain: Yeah.
Ashim Matthan: Okay. So, that leads us to topic number two, which is — What is an AI?
Kanishka Jain: What is an Aromatase Inhibitor?
Ashim Matthan: Right. So Aromatase is the enzyme in the body that converts excess Testosterone to Estrogen. The excess Testosterone is going to be different from person to person. It’s also going to be different for you within your lifespan in the sense that on a day to day basis. For example, there are lots of triggers which can convert Testosterone to Estrogen. You’ve got.. if say for example, you fall sick and you take a certain antibiotic. That could be the trigger. So you’re taking other chemicals on top of Testosterone those could also be the trigger. So there are various things that come with it. It’s just that this is your threshold limit and beyond that whenever your body registers or there is too much Testosterone, I better convert it to Estrogen. And then it will get converted to Estrogen. That’s what Aromatase does as an enzyme.
Kanishka Jain: Yes. So why do people run Aromatase Inhibitors on a cycle?
Ashim Matthan: Because the most problematic thing that any AI will do, there are lots of side-effects that AI… of high Estrogen, some of them are like cosmetic, like people get lot of flushing of the skin, stuff like that, which most people would not care about. But the thing that you will care about, that most of us should as men care about is that it can go into your chest, into your breast tissue and make it into Gynecomastia.
Kanishka Jain: Yes. Also, in addition to that, it can cause bloating and it can take away from the lean muscular look that you’re aiming for when you’re running a Test blast.
Ashim Matthan: Right, exactly. Yes. So the reason why people would want an AI on hand is more so because of the gyno as priority number one, the most dangerous thing that they would put it down to.
Kanishka Jain: And so, what is DHTs and what is its role with Estrogen?
Ashim Matthan: So, DHTs are your end product of Testosterone. In the life-cycle of Testosterone in your body the finished product would be DHTs and so firstly Proviron is a very weak DHT, it’s a poor DHT. And what DHTs do, is that they also similar to Estrogen just roam around your body. It’s a product of your free Testosterone.
Kanishka Jain: Yeah. So Dihydrotestosterone or DHTs are like Proviron, Masteron, which is Drostanolone. And other compounds, which are used in a lean gaining cycle or a lean cutting cycle where they work to displace Estrogen from your system and give you the Androgenic manly look that you’re looking for and the lean cut look.
Ashim Matthan: Right. So, the reason why you would want to take a DHT instead of an AI, so we firstly, let’s go back a little bit. We don’t like AIs.
Kanishka Jain: Yes, we don’t like AIs.
Ashim Matthan: We don’t like AIs, there were lot of side-effects and it’s not a good long-term to take the AIs. If you must take an AI, it should be done short-term. We’ll get into that at the end. So you don’t want to take an AI. So you take a DHT because the same receptors that Estrogen sits on is the same receptor where a DHT can kick Estrogen out of and occupy that space, right?
Kanishka Jain: Yeah. Because in addition to that, because DHTs are most sensitive for those receptors, the androgenic receptors. Those are the ones which are DHT on them when they are not, when the DHT is not there, it will have an Estrogen market.
Ashim Matthan: Correct. So it’s not possible for each Estrogen to kick a DHT out of their receptor, but it’s possible for a DHT to kick an Estrogen out.
Kanishka Jain: Yes.
Ashim Matthan: So that’s why they say that if you have gyno, and if you want to know whether the Masteron that you have on hand is good quality, high quality Masteron, you can blast Masteron and Masteron should reverse the gyno on its own, you should not need any AI. That’s the thing, that’s why he wants Proviron because in the list of DHT analogs Proviron is one of them.
Kanishka Jain: Yes, correct.
Ashim Matthan: Okay. So if you have an AI, so what, how would we do this? Like, because… let’s go back to this question. The fundamental root cause of this problem because he doesn’t want high Estrogen levels, which he feels are going to happen when he takes a high amount of Test. So he wants to keep Proviron on hand as an AI. So short and simple answer is Proviron a good AI?
Kanishka Jain: No. So, in our experience, Proviron is not a good AI. It is a weak DHT. Thus it becomes a weak AI. It cannot displace Estrogen and prevent gyno. It can be an add-on to TRT for some people when they’re running small doses of TRT and they want a sudden look.. like they want a cut lean look. You can run Proviron for a short period of time, but you we wouldn’t suggest that.
Ashim Matthan: So, just to get certain things clear, DHTs are also bioidentical hormones.
Kanishka Jain: Yes.
Ashim Matthan: And Proviron falls into that category, but it’s a weak synthetic version of that Masteron or any of the others will be cycling more powerful, better, more closer to the original real deal. So if you want to have like a flow chart of how you go about selecting something like this first you want to know is do you value your hair. Obviously you and I know don’t but say someone does value their hair then they’re going to say that they’re not, then they will not want Masteron or even Proviron because it can trigger hair loss, right.
Kanishka Jain: Yes. So, if you are at risk of it, that is if your dad, your brother or anybody in your family or if you have any experience of running these compounds before, and they’ve caused hair loss, then definitely Masteron is not the answer for you.
Ashim Matthan: Right. Even if you have, normally we do blood tests, right? The DHT test that we do, And if the values are very high, close to 900. Then we say that, okay, you’re at risk of it. Yes. You probably should stay away from these things. So if your career or whatever if you care about your hair fall, don’t get into these DHTs, it’s a risk that you’re taking. In order for them to take care of… to be an AI, you can take the DHTs and you have to take a whole bunch of precautionary measures to run them and protect your hair from falling. But as an AI, it’s not the first thing that we want to use them in that case, because these are the values that we have. So if you care about hair fall, don’t get into this. If you don’t care about hair fall then DHT, a good strong DHT is a good AI.
Kanishka Jain: Yeah. So if you don’t care hair fall or if you are not at risk of having any hair fall then run these compounds, then you can try a compound for some time, like a Masteron or something and see that are you getting hair fall on it. If you’re getting hair fall on it, so hair fall is more than 100 hair follicles a day, yeah so a fall of more than 100 hair follicles a day because that is our turnover of hair. So, if you’re exceeding that amount, you should be very wary of using Masteron if you value your hair.
Ashim Matthan: So, let’s look here, let’s say that someone who had, so whenever you run any of these chemical compounds, you should have a doctor who is monitoring you, it’s good for… it’s just safety. In India, it’s the legal way of doing it. If you want to run steroids, anabolic steroids, you should have a doctor who is going to monitor you. So, say we have a patient, say we have a case, a patient, who wants to increase his Test usage. How would we go about it? How would we systematically do it in a safe manner? The emphasis of course would be safety first.
Kanishka Jain: So, lets say that if somebody came like that and he’s done a cruise right now, you would not straight away taper the dose upto 500. That is a shock on the body. You slowly, slowly taper up, you keep your doses very, very frequent — you don’t give big, big surges of Testosterone. You use a slow picking esther like Enanthate or Cypionate. And week to week you can start at 200 then go up to 250 then 300, 350. And as soon as you start experiencing effects of Estrogen or high Estrogen, you know, that is the time that you should have an AI on hand to run it.
Ashim Matthan: Right. So you would keep let’s say Armotraz or Arimidex or Aromasin you keep some of these things on hand, whichever agrees with you because everybody is different. You have to know which one works for you which one doesn’t. We like Aromasin because it peaks in an hour, right? So you know that as soon as you take it, whether or not you should start feeling better. So it’s one of those compounds Exemestane.
Kanishka Jain: Exemestane.
Ashim Matthan: Is just a chemical term.
Kanishka Jain: Yeah. So, we have AIs and we have weak AIs which are SERMS, which go and target only the breast tissue. We should have both on hand. So something like Tamoxifen or a Nolvadex can also work as an AI to prevent just gyno. But the other effects are not going to be reversed of high Estrogen. So what are the other effects of high Estrogen that a gyno notices when they are doing AI?
Ashim Matthan: You’ll get bloating. Yes. A lot of bloating, water retention, you get flushing of the skin. Yes. Right? And Estrogen levels jumping all over the place can also cause like a fluctuation in your sex drive, in your libido.
Kanishka Jain: Yes.
Ashim Matthan: And in your paranoia.
Kanishka Jain: Yes.
Ashim Matthan: And irritability.
Kanishka Jain: So, let’s say that you’re at risk of dying. Let’s say that you’re running 300 milligram of Testosterone, you’re not even tapered up to 500. The first time that you may see is itchy burning nipples.
Ashim Matthan: Yeah.
Kanishka Jain: As soon as you notice that and that means that even when a t-shirt touches it, you will just scream in pain. That is how much sensitivity it induces. Because Estrogen is not what our body likes, a man’s body does not want Estrogen.
Ashim Matthan: Beyond the point.
Kanishka Jain: Beyond the point. It’s very good, it’s anabolic, it’s very good for us.
Kanishka Jain: It has Nootropic effects in the normal range.
Ashim Matthan: Yeah. And if you have Estrogen in good ranges, it should have all the benefits of Estrogen, none of the bad side effects… we want that. We don’t want it to beyond, in too much of an excess and that will cause all of these bad reactions to start happening. But the second you notice that oh yeah, I’m getting that my nipple is a little sensitive, don’t do it. Start your AI post immediately.
Kanishka Jain: Yes. So let’s say that you are at 500 milligrams a week, and you had no gyno…
Ashim Matthan: No.. I’m going to interrupt you, sorry. Can you scale back, let’s say that we’re at 300, I’m at 300, and I started noticing that okay, my nipple is a little sensitive, so what should I do.. what’s the first thing that I do?
Kanishka Jain: So, the first thing is that, let’s say that you have Letrozole on hand, Letrozole is one of the most, cheapest AIs available out there. You take one tablet of it, it peaks in the blood within 4 to 6 hours.
Ashim Matthan: Okay.
Kanishka Jain: Let’s say that you took it in the night the next day morning your gyno should be better.
Ashim Matthan: But do I take my shot?
Kanishka Jain: Yeah.
Ashim Matthan: So, what we normally do is whether you’re on TRT or whether you’re blasting or whatever you’re doing, we like very, very frequent injections as frequent as possible. So let’s just say that you are one of those people who is able to handle seven days a week. So you have seven injections a week. So everything is going to be in multiples of seven. So your TRT dose will not be 200. It’ll be like 210. Then if your blast also might not be 500, it might be 490. So, it’s going to be stuff like that. You’ve got to like, take this, you’ve to like do these small calculations, but this is the intricacies of it. So if you say I’m supposed to take an injection today, I felt that gyno yesterday, I was at 300 and I took my AI, I took Letroz at night. And this morning I wake up and I still feel that there is a little bit of gyno, it’s improved but it’s still there. So, what am I supposed to do?
Kanishka Jain: So let’s say that you took a Letrozole in the night.
Ashim Matthan: Yeah.
Kanishka Jain: Your gyno has gone away. You will take your shot the next day. Letrozole lasts in your system for three days.
Ashim Matthan: But what if it’s not gone? What if it’s still there?
Kanishka Jain: So, if it’s still there, I will repeat the dose of Letrozole the next day.
Ashim Matthan: Okay. And what about the Test?
Kanishka Jain: And the Testosterone shot as well
Ashim Matthan: Okay.
Kanishka Jain: The next shot will be taken with this thing. Because the effect of Letrozole is best when there is Testosterone running in the system so that it can start countering the Estrogen.
Ashim Matthan: Also, you don’t want to stop the Test suddenly because it will be a drop and there is no need to subject it to these shocks.
Kanishka Jain: Yes.
Ashim Matthan: You wanted the levels to be as stable as possible. Right?
Kanishka Jain: Yeah. So option one would be that you take your Test shots every day and you take the Letrozole. Letrozole is a very strong AI, it is going to reverse your gyno at one point or the other. So, for the dosing, you have to find out that at what dose it working, with the Testosterone dosing because you’re not going off the Testosterone.
Ashim Matthan: Right.
Kanishka Jain: So, ideally, let’s say that it is one tablet every 3 to 4 days that works for most people. You may be an anomaly and it may be 3 tablets in 7 days that you need to take based on how your gyno is progressing or if your gyno is not improving at all.
Ashim Matthan: Right. So.. we actually deviated a little bit from the topic, but as is this is going to happen. So, back to this gentlemen’s question, The answer is — Proviron is not what we recommend.
Kanishka Jain: Proviron is not going to prevent your gyno.
Ashim Matthan: Yeah. It’s not going to prevent his gyno, it’s not even going to be a good AI nor is it going to be a very good DHT, especially not at that dosage. Like if you’re going to be taking 500 mg of Test a week, then you’re like in the big-boy league. So you should be having big-boy compounds also that are there with you. Proviron is very, very weak. So, you want to take Masteron or you want to take any of the others that are there instead.
Kanishka Jain: Yes.
Ashim Matthan: Okay. And I think this is the answer to the question for the day. Thanks a lot for watching. If you have any questions, please go ahead and ask them. Thank you.
Kanishka Jain: Thank you.
Ashim Matthan: Hi everyone. Welcome to the RhinoMight podcast. My name is Ashim. This is Dr. Kanishka. So, today’s question is going to be about using Anavar and Clen for fat loss for women. So, this question was posted on steroidsxx. And this lady wants to know if she can use Anavar and Clen to drop body fat because she wants to look good. She wants a boost to confidence and she wants to go on holiday in November. And she’s 97 kilos in weight and she is 5 feet 11 inches tall. And she wants to take/add Clen to her Anavar stack because she thinks it’s going to help with her weight loss. She’s doing strength training in the gym, and she’s going to be maintaining a calorie deficit. And she’s mentioned strength training and calorie deficit. What I think of is that she’s extremely proactive as a patient, a really good patient to have. She seems to be really on top of her game with, in terms of for her investment into herself, her goals. So, yeah, what’s the short answer?
Dr. Kanishka Jain: Short answer is definitely, you can use these compounds.
Ashim Matthan: Like these compounds are great. Anavar and Clen, have been used before for fat loss. They have a weird sort of synergy, it’s not the type of synergy that we would play with but it is good because Anavar is like a recomping agent. It’s going to also make her hit in new PRs, she is going to love the feeling of it because it’s going to make her very, very strong. So, performance wise in the gym she is going to be performing very well, she is going to probably set new PRs. And that’s going to make her very happy. And Clen on the other hand is a fat burner, Clen is a wonderful oral tablet, both of these are oral tablets.
Dr. Kanishka Jain: Yeah. So, we wouldn’t plan this in that way.
Ashim Matthan: This is not the way we would go about it at all. I know that, so the one thing that we have to take into account is, in our system we have to sort of like change it because she has a deadline where by November she has to bring her A-Game to the table. So she has to be her really, really good by November. And I think she has quite a bit of fat loss to have, she’s mentioned it’s quite a bit. Yeah, that’s what she describes it. So, we’re looking at a lot of fat loss, we also got to assume with that fat loss that there’s a lot of skin… lose skin that would form so we’d have to tighten that up. And then, okay, so let’s go, how would we do it? Let’s make steps.
Dr. Kanishka Jain: Yeah, so our plan would be that step one that we would use HRT. She has not mentioned that she’s using HRT or not but we would start with HRT where we use three sex hormones which are bioidentical for woman that is Testosterone, Estrogen and Progesterone, where Estrogen would be done in the form of gels, Progesterone would be done in the form of tablets or gels and Testosterone would be done in the form of either gels or injections.
Ashim Matthan: Yeah. We prefer injections. That’s sort of like preferred choice because it’s the best bang for your buck. And as long as the patient is okay with needles and she’s not apprehensive and scared about them. And I think that this lady in question is not very comfortable about needles because both the chemicals that she’s talked about are oral tablets. We have no idea what her medical history is. All we know, she could be already on HRT, but if HRT is dialed-in correctly, it should already cause a significant amount of body change. And her boost in confidence should happen with HRT. We would know that we’ve done a good job with HRT if she’s already… if we check off these two points, these two goals of hers, it means that we’re on the right track.
Dr. Kanishka Jain: Yeah, with a good dialed-in HRT she would meet her goals.
Ashim Matthan: Especially because she’s doing strength training and which means she has activity and she’s also going to be maintaining a good diet. So all the more reason for this to work synergistically well with that.
Kanishka Jain: Yeah.
Ashim Matthan: Okay, so step one, we play with HRT, these three compounds, Progesterone, Estrogen and Testosterone. Step two, is that we add Hormone Supplementation to that. We play with T3 and T4.
Kanishka Jain: These are the complete Thyroid Supplementation.
Ashim Matthan: Right.
Kanishka Jain: So, that would be done in the form of tablets as well. Right? Yes.
Ashim Matthan: So, these are oral tablets. And also, I just want to move a little bit off track, but I want to mention, she’s talked about using Clen. You would never take Clen, we would never advice Clen without T3 and T4. We’re also going to mention Growth Hormone just a little bit down the line. And if you’re going to be using Clen and Growth Hormone, you always take thyroid supplementation with that.
Kanishka Jain: Yeah, to maximize. They work in a synergistic system, right?
Ashim Matthan: Also, that if you take Clen and Growth Hormone, they tend to burn off your T3 or T4.
Kanishka Jain: Yeah.
Ashim Matthan: And then you want to make sure that supplementation is going on so that you have the best effects.
Kanishka Jain: Yeah. You’re getting like the maximum effects from these kinds of compounds.
Ashim Matthan: Right. So, step one — HRT. Step two — HRT plus Thyroid Supplementation. Step three — HRT plus Thyroid Supplementation plus if she can afford it, we would do IGF4 level test and we would supplement Growth Hormone. If she cannot afford Growth Hormone, then we would do Clenbuterol as the next option. And if she can afford both then we would add GH and Clen. So, 3a is like GH, 3b is Clen, 3c is Clen plus GH, both of them being used.
Kanishka Jain: So, and I think Step four would be just all of these things plus Anavar in the recomp.
Ashim Matthan: Yes, the full package.
Kanishka Jain: Yeah, the full package.
Ashim Matthan: But if we do our job properly, she would not need to go to step four. I think that, see when you’re talking about like fat loss, Growth Hormone, its strategic value, it is a wonderful tool for fat loss. It is the best fat burning agent. We like it as a slow fat burning. But it is slow. Right now we’re running on a deadline. She wants to be like all set by November. So we’d have to play it a little differently.
Kanishka Jain: Yeah. We’re going to have to play a little differently where we do the HRT, we optimize her, we keep reassessing her after every month, every two to three weeks actually, because we are running on a deadline.
Ashim Matthan: Yeah. So we would… Sorry, go on.
Kanishka Jain: Yeah, and we would wait for the optimization to happen. In two to three weeks, we are able to judge that, is this patient responding very, very well to the dose, which has been there. Our first step would be to not add more compounds, but to increase the dose of the compounds that she already has, get them optimized and then decide if something else needs to be added to this protocol or not.
Ashim Matthan: Exactly. So like, you know, most women are very, very scared who’ve got Testosterone, they’re very apprehensive, because they feel it’s going to make them very manly and there’s going to be virilization that’s going to take place.
Kanishka Jain: Yeah. Like growth on the face.
Ashim Matthan: Yeah, hair growth on the face.
Kanishka Jain: Hair growth on the face.
Ashim Matthan: Right.
Kanishka Jain: Manly voice.
Ashim Matthan: Deep husky voice is going to start they’re worried about their clit as well. And like, what you have to do is, when you’re taking these compounds, you have to be very self-vigilant, self-monitoring yourself. If you start noticing that something’s out of whack, like you’re getting hair growth where you didn’t have it before or anything like that, you have to immediately dial-down the dose. So all of these side-effects take place when the dose is too much. So, the antidote to a high dose is that you cut down on your dose and it sort of corrects itself if you do it early on. If you wait and you… because you know what happens with Testosterone, high Testosterone means high libido.
Kanishka Jain: Yes.
Ashim Matthan: Okay, so they’re going to enjoy a great sex life, and they might be carried away with it initially and they might go, like oh, it’s little bit of hair growth, it’s okay, I’m having a lot of sex, I’m enjoying it. So why not? And it’s fine. I’ll do my waxing or bleaching or whatever it is that they prefer. And they sometimes let things slide. But long-term that’s not the right thing to do because if you keep any of these side-effects in play, for long-term, they would become permanent. And the way to avoid them becoming permanent is that as soon as they start showing themselves, STOP. Cut back on your dose. So we normally take a very, very low dose of test to start with for.. 5…
Kanishka Jain: 5 mg to 25 mg per week.
Ashim Matthan: Exactly. So 5 mg to 25 mg per week, which is very minuscule compared to what gentlemen, for what men use. So with ladies it’s 5 to 25 and sometimes depending on the preference of the patient we can do like daily injections of like 1 mg to 2 mg every day on a short acting ester or medium acting ester, because Testosterone Enanthate will keep compounding on itself in effect. It just takes a while for Testosterone, that’s all. But whether it is Testosterone Enanthate or Propionate it doesn’t really matter. We stay away from Sustanon and long acting mixture of Esters. We stay away from that.
Kanishka Jain: Yeah, we keep the release of the Testosterone very, very stable. We don’t allow the fluctuations to happen. So that’s how you avoid the side effects of the fluctuation of Testosterone.
Ashim Matthan: Exactly. And also with like Sustanon, we don’t know if the mixture is homogenous or not, like, which means that If say Sustanon has four different Esters that are there in it, four different Testosterone Esters, and they’re not in equal proportion. So if you are taking out a small amount, so within this in-equal proportion of Testosterone Esters, in a say, 1ml vile of it, you don’t know whether like every little bit of it that you take out has them in the same proportion.
Kanishka Jain: And you’re not able to predict the peaks with that.
Ashim Matthan: Exactly. So things could go out of whack and you don’t want those types of levels to take place. So we like to play with Test Cyp, Test Prop or Test Enanthate. You stick to one of these three. And if the patient is very, very apprehensive and does not want to use injections, we go with gels and gels are the next best option on the table.
Kanishka Jain: Yes.
Ashim Matthan: Okay. So, we optimize these three levels.
Kanishka Jain: So, can we just do a summary of what-what we will do as steps?
Ashim Matthan: Yes.
Kanishka Jain: So for this patient who’s 97 kilos, who’s 5’11, wants to lose weight, is on a time crunch, wants to get in shape by November, our step one should be HRT with three sex hormones that is, Estrogen, Progesterone, Testosterone. Then on that, on the top of this after reassessment, we would want to add T3, T4. And if these things are also not able to have the desired effect that you want, you would want GH. Another thing that we forgot to add, GH also causes lot of skin tightening. So, when you lose a lot of body fat, you’re going to have a lot of loose skin. So to tighten that GH will help. It lays down good tissue which is going to tighten everything.
Ashim Matthan: Right. So, all of her womanly curves and the confidence that she wants could be further accentuated and she would definitely want that.
Kanishka Jain: Yes. So, on top of that, if you cannot afford GH, we would run Clen or we would run Anavar on top of everything else afterwards, that would be our step four, that will be our last step.
Ashim Matthan: Yes. So, all of these chemicals work really well as, like in synergy until you get that Anavar because Anavar is more like, I won’t say muscle building, but it’s like a recomping agent, more of a recomping agent. So in some senses like she would be able to perform better and therefore be more active, whether in a roundabout way, because she’s going to be more active if she burns up more calories so stamina-wise she would increase. Yes. There would be an increase. And that’s what she will do. But if we’ve done our job properly, if we have optimized our hormones, if we’ve played with thyroid correctly, and if we have GH or Clen and/or Clen to play with, then that’s good enough. You would not need anything else. The only problem is that this is on a time crunch. So if she loses too much weight, there might be like loose skin, in which case using Anavar is wise, because it would cause like a little bit of hardening of the muscles, a recomping thing which would tighten… it will somehow cosmetically tighten it up more than Growth Hormone because Growth Hormone doesn’t work in such short burst of time if you don’t want to overload GH. Even though sometimes when we use GH we do front load a little bit but with the Growth Hormone, those are like really, really tiny compared to what we use for men.
Kanishka Jain: Yeah. Like, let’s say that in comparison, a woman’s dose might be like 0.25 IU a day, that’s not even like one fourth, it’s usually one fourth of a guy’s dose.
Ashim Matthan: Exactly. So, this is how we do it. So, yeah. You want to add anything else to this?
Kanishka Jain: Just the T3, T4 that we forgot to discuss. With T3, T4, we could always have controlled chaos protocol, where we taper off the dose slowly and we take it down, very, very slowly so that there are, no long-term hypothyroidism or there is no long-term side-effects of it.
Ashim Matthan: Exactly. So, thyroid is a gland that is extremely resilient. So if you are responsible with your T3, T4 medication and supplementation, it’s very, very unlikely, almost unheard of, I won’t say impossible so I will say extremely unlikely and unheard of for someone to develop Hypothyroidism because of, responsible, T3, T4 supplementation.
Kanishka Jain: So, the goal is, in short, that you go slow, be steady, you reassess and then you decide to add other compounds.
Ashim Matthan: Yeah. So we would go about like that. And almost everything is bioidentical for a large chunk of this. Your three sex hormones are bioidentical hormones, your T3, T4 is also bioidentical. And then you have Growth Hormone, also bioidentical. So, within the spectrum of bioidentical hormones before you get Clen, as Clen is not there in your body. It’s not bioidentical. And then Anavar also, same principle applies. It’s not part of your system. So these are like foreign substances that you bring to the table, maybe towards the end. But because you’re on a time crunch, we would consider them to be added in maybe early on just to see.. just because we don’t have the luxury of waiting for Growth Hormone to take its actual results and bring them to the table.
Kanishka Jain: Or if you see that the goals are not being met.
Ashim Matthan: Yeah.
Kanishka Jain: Like what we expect them to be like, what we expect the results and they are not meeting those requirements. And we can definitely add Clen, Anavar and these compounds but in a very controlled manner, in a very, very monitored manner.
Ashim Matthan: Right. Okay. So that’s all for today. Thanks a lot for watching this video. If you have any questions, please feel free to ask us. And we’ll see you next time. Thank you.
Kanishka Jain: Bye.